Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987538 | 0.72 | BACE1 (0.41) | BACE1HDAC4OPRM1OPRD1OPRK1 | |
| SCHEMBL12475301 | 0.72 | BACE1 (0.39) | BACE1HDAC4OPRM1OPRD1OPRK1 | |
| SCHEMBL7571494 | 0.72 | P2RX7 (0.35) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL26685809 | 0.70 | — | — | |
| SCHEMBL17982784 | 0.68 | HDAC4 (0.38) | BACE1HDAC4OPRM1OPRD1OPRK1 | |
| SCHEMBL18021960 | 0.68 | OPRM1 (0.51) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL2461591 | 0.68 | PDE10A (0.42) | BACE1PDE10A | |
| SCHEMBL21937614 | 0.67 | HDAC4 (0.40) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL28014947 | 0.67 | SLC6A4 (0.32) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4006359 | 0.66 | ALDH1A1 (0.37) | BACE1HDAC4OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2672982-A2 | GHRELIN MIMETIC POLYPEPTIDE HAPTEN IMMUNOCONJUGATES HAVING IMPROVED SOLUBILITY AND IMMUNOGENICITY AND METHODS OF USE THEREOF | The Scripps Research Institute (US) | 2013-12-18 | — | — | EP | claimed |
| WO-2012108960-A2 | GHRELIN MIMETIC POLYPEPTIDE HAPTEN IMMUNOCONJUGATES HAVING IMPROVED SOLUBILITY AND IMMUNOGENICITY AND METHODS OF USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-08-16 | — | — | WO | claimed |