Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543238 | 1.00 | OPRL1 (0.33) | OPRL1OPRM1P2RX7RAF1ICMT | |
| SCHEMBL31543237 | 0.87 | OPRL1 (0.33) | OPRL1OPRM1RAF1ICMTCYP2D6 | |
| SCHEMBL21329961 | 0.82 | P2RX7 (0.31) | OPRM1P2RX7 | |
| SCHEMBL21330013 | 0.82 | P2RX7 (0.35) | OPRM1P2RX7RAF1ICMTCYP2D6 | |
| SCHEMBL31568028 | 0.77 | PKLR (0.33) | — | |
| SCHEMBL26685809 | 0.72 | — | — | |
| SCHEMBL20436491 | 0.71 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL31568035 | 0.71 | TYK2 (0.42) | — | |
| SCHEMBL26685551 | 0.71 | — | — | |
| SCHEMBL29017386 | 0.70 | SLC6A3 (0.42) | OPRM1P2RX7ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220046-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2023-11-16 | — | — | WO | disclosed |