Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.42 |
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | DRD3 | P35462 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686896 | 0.84 | ALOX15 (0.52) | DRD4DRD2DRD3HTR2AHTR7 | |
| SCHEMBL26686721 | 0.84 | ALOX15 (0.52) | DRD4DRD2DRD3HTR2AHTR7 | |
| SCHEMBL26686741 | 0.82 | LRRK2 (0.52) | DRD4DRD2DRD3HTR2AHTR7 | |
| SCHEMBL26686799 | 0.82 | METAP2 (0.49) | DRD4DRD2DRD3HTR2AHTR7 | |
| SCHEMBL26686599 | 0.79 | DRD4 (0.43) | DRD4DRD2DRD3HTR2AHTR7 | |
| SCHEMBL26686804 | 0.78 | POLB (0.50) | DRD4DRD2DRD3HTR2AHTR7 | |
| SCHEMBL26889310 | 0.72 | CCNK (0.42) | DRD4DRD2DRD3MAP3K11CDK9 | |
| SCHEMBL20757525 | 0.70 | LRRK2 (0.53) | LRRK2CDK2CDK9CDK5CCNT1 | |
| SCHEMBL2693766 | 0.70 | LRRK2 (0.53) | CYP1A2CYP2D6LRRK2CDK2CDK9 | |
| Hydrochloric Acid SCHEMBL30705239 | 0.69 | LRRK2 (0.51) | CYP1A2CYP2D6LRRK2CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |