Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | CHKA | P35790 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686799 | 0.95 | METAP2 (0.49) | POLBKDM4EALDH1A1TDP1DRD2 | |
| SCHEMBL26686896 | 0.87 | ALOX15 (0.52) | POLBKDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL26686721 | 0.87 | ALOX15 (0.52) | POLBKDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL26686599 | 0.82 | DRD4 (0.43) | POLBALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL26686741 | 0.80 | LRRK2 (0.52) | POLBDRD2DRD4DRD3ROCK2 | |
| SCHEMBL26686759 | 0.78 | DRD4 (0.42) | POLBDRD2DRD4DRD3ROCK2 | |
| SCHEMBL26889381 | 0.74 | CCNK (0.54) | POLBKDM4EALDH1A1TDP1CHKA | |
| SCHEMBL14907882 | 0.72 | ALOX15 (0.49) | KDM4EDRD2DRD4DRD3ROCK2 | |
| SCHEMBL2693766 | 0.72 | LRRK2 (0.53) | ROCK2ROCK1CDC42BPBCDC42BPACYP1A2 | |
| Hydrochloric Acid SCHEMBL30705239 | 0.70 | LRRK2 (0.51) | ROCK2ROCK1CDC42BPBCDC42BPACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |