Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 4/20 | 0.97 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.97 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.97 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 0.97 |
| ▸ | DPP4 | P27487 | 1/20 | 0.97 |
| ▸ | MEN1 | O00255 | 1/20 | 0.97 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.97 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.97 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.97 |
| ▸ | GAPDH | P04406 | 1/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.97 |
| ▸ | STAT6 | P42226 | 1/20 | 0.97 |
| ▸ | PI4KA | P42356 | 1/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.97 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.97 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.97 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.97 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.97 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL12222448 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL2028876 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL329845 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23420216 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Vidarabine SCHEMBL110914 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL23804425 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL2403831 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL24538665 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL4403412 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 | |
| Adenosine SCHEMBL10361572 | 0.99 | ADORA3 (1.00) | ADORA3DPP4MEN1SLC28A1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661603-A | Production process of adenosine cyclophosphate | 海南卓科制药有限公司 | 2025-03-21 | — | — | CN | disclosed |
| WO-2023220236-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS | AMYLYX PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-116601145-A | Potent and selective calcium-activated potassium channel K for plateau treatment Ca 3.1 inhibitors | 南洋理工大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-113173984-B | Application of novel photosensitive channel protein VR1.0 in preparation of medicine for treating retinal photoreceptor cell degenerative disease | 中眸医疗科技(武汉)有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113173984-A | Application of novel photosensitive channel protein VR1.0 in preparation of medicine for treating retinal photoreceptor cell degenerative disease | 武汉大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110016069-A | Tanshinone IIA piperazine compounds and its preparation method and application | 上海星叶医药科技有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-103495173-B | Trauma care | 低温药理KF有限公司 | 2016-11-23 | — | — | CN | disclosed |