Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 8/20 | 0.44 |
| ▸ | CTSL | P07711 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669261 | 0.88 | F10 (0.45) | F10CTSSCTSLGCKPYGL | |
| SCHEMBL2669063 | 0.81 | CTSL (0.47) | CTSSCTSLCTSKGCKPYGL | |
| SCHEMBL2669288 | 0.76 | GCK (0.53) | KCNH2GCK | |
| SCHEMBL2669228 | 0.75 | CTSL (0.46) | CTSSCTSLCTSKGCKPYGL | |
| SCHEMBL2520055 | 0.71 | GCK (0.60) | GCK | |
| SCHEMBL2669248 | 0.71 | GCK (0.41) | CTSSCTSLCTSKGCK | |
| SCHEMBL2669291 | 0.70 | SMN1; SMN2 (0.45) | CTSSCTSLCTSKGCKPYGL | |
| SCHEMBL2669154 | 0.69 | CTSL (0.43) | CTSSCTSLCTSKGCK | |
| SCHEMBL9072816 | 0.69 | CTSL (0.45) | CTSSCTSLCTSKGCKPYGL | |
| SCHEMBL2434887 | 0.69 | F10 (0.75) | F10KCNH2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |