Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | GCK | P35557 | 3/20 | 0.40 |
| ▸ | PPM1D | O15297 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669154 | 0.90 | CTSL (0.43) | CTSLUSP30CTSSGCKPPM1D | |
| SCHEMBL9072816 | 0.90 | CTSL (0.45) | CTSLUSP30CTSSGCKPPM1D | |
| SCHEMBL2669300 | 0.89 | CTSL (0.43) | CTSLUSP30CTSSGCKPPM1D | |
| SCHEMBL9072791 | 0.86 | CTSL (0.41) | CTSLUSP30CTSSGCKPPM1D | |
| SCHEMBL2669250 | 0.86 | PSEN1 (0.44) | CTSLUSP30CTSSGCKPPM1D | |
| SCHEMBL2669260 | 0.85 | PSEN1 (0.43) | SMN1; SMN2CTSLCTSSGCKCTSK | |
| SCHEMBL2669262 | 0.85 | PSEN1 (0.51) | SMN1; SMN2CTSLCTSSF2RL1CTSK | |
| SCHEMBL2669063 | 0.84 | CTSL (0.47) | CTSLUSP30CTSSGCKF2RL1 | |
| SCHEMBL2669256 | 0.84 | CTSS (0.46) | CTSLCTSSGCKF2RL1CTSB | |
| SCHEMBL9072817 | 0.84 | OGA (0.44) | SMN1; SMN2CTSLCTSSGCKCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |