Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.41 |
| ▸ | PPM1D | O15297 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669063 | 0.93 | CTSL (0.47) | CTSLGCKPYGLUSP30CTSS | |
| SCHEMBL2669306 | 0.88 | F10 (0.46) | F10CTSLGCKPYGLCTSS | |
| SCHEMBL2669228 | 0.87 | CTSL (0.46) | CTSLGCKPYGLUSP30CTSS | |
| SCHEMBL2669291 | 0.81 | SMN1; SMN2 (0.45) | CTSLGCKPYGLUSP30PPM1D | |
| SCHEMBL2669154 | 0.80 | CTSL (0.43) | CTSLGCKUSP30PPM1DCTSS | |
| SCHEMBL9072816 | 0.80 | CTSL (0.45) | CTSLGCKPYGLUSP30PPM1D | |
| SCHEMBL2669300 | 0.79 | CTSL (0.43) | CTSLGCKUSP30PPM1DCTSS | |
| SCHEMBL2669288 | 0.78 | GCK (0.53) | GCK | |
| SCHEMBL2669250 | 0.77 | PSEN1 (0.44) | CTSLGCKUSP30PPM1DCTSS | |
| SCHEMBL9072791 | 0.77 | CTSL (0.41) | CTSLGCKUSP30PPM1DCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |