SCHEMBL26693248

SCHEMBL26693248

N[C@@H](Cc1c[nH]c2cc(Br)c(Br)cc12)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.64
BLM P54132 4/20 0.64
KDM4E B2RXH2 4/20 0.64
MAPT P10636 4/20 0.64
LMNA P02545 3/20 0.64
PMP22 Q01453 3/20 0.64
NPSR1 Q6W5P4 3/20 0.64
NFKB1 P19838 3/20 0.64
TSHR P16473 2/20 0.64
ALDH1A1 P00352 2/20 0.64
CYP3A4 P08684 2/20 0.64
ALOX15 P16050 2/20 0.64
HSD17B10 Q99714 2/20 0.64
HTR1A P08908 2/20 0.64
HTR2A P28223 2/20 0.64
HTR2C P28335 2/20 0.64
HTR2B P41595 2/20 0.64
ADORA3 P0DMS8 1/20 0.64
SLC6A4 P31645 1/20 0.64
HTR7 P34969 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26693252 1.00 KMT2A (0.64) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL7763037 0.84 KDM4E (0.70) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL274624 0.83 KMT2A (0.66) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL8502601 0.83 KMT2A (0.66) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL30381776 0.83 KMT2A (0.66) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL29855626 0.83 KMT2A (0.66) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL274625 0.83 KMT2A (0.66) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL307776 0.83 KMT2A (0.73) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL30405928 0.83 KMT2A (0.73) KMT2ABLMKDM4EMAPTLMNA
SCHEMBL19871231 0.83 KMT2A (0.73) KMT2ABLMKDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250354108-A1 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS UNIV DANMARKS TEKNISKE (DK) 2025-11-20 US disclosed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP disclosed
WO-2023222879-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250354108-A1 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS INMT, KARS1, MIA3 KMT2A 445/4885BLM 726/4885KDM4E 2243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.