SCHEMBL274624

SCHEMBL274624

N[C@@H](Cc1c[nH]c2cc(Br)ccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
KDM4E B2RXH2 4/20 0.66
MAPT P10636 4/20 0.66
BLM P54132 4/20 0.66
LMNA P02545 3/20 0.66
PMP22 Q01453 3/20 0.66
MEN1 O00255 3/20 0.66
TSHR P16473 2/20 0.66
HIF1A Q16665 2/20 0.66
MPO P05164 1/20 0.66
PTPRA P18433 1/20 0.65
CYP2C19 P33261 1/20 0.62
NPSR1 Q6W5P4 3/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
NFKB1 P19838 2/20 0.61
HSD17B10 Q99714 2/20 0.61
HTR1A P08908 1/20 0.61
ADORA3 P0DMS8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30381776 1.00 KMT2A (0.66) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL274625 1.00 KMT2A (0.66) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL29855626 1.00 KMT2A (0.66) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL8502601 1.00 KMT2A (0.66) KMT2AKDM4EMAPTBLMLMNA
Tryptophan SCHEMBL17165924 0.89 KMT2A (0.71) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL19871231 0.89 KMT2A (0.73) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL30405928 0.89 KMT2A (0.73) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL29382361 0.89 KMT2A (0.73) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL454983 0.89 KMT2A (0.73) KMT2AKDM4EMAPTBLMLMNA
SCHEMBL307776 0.89 KMT2A (0.73) KMT2AKDM4EMAPTBLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022515-A2 PROCESS FOR DYEING TEXTILES SANKO TEKSTIL ISLETMELERI SAN VE TIC AS (TR) 2026-01-22 US claimed
EP-4110328-B1 INTERVENTION STRATEGY FOR PREVENTION OR TREATMENT OF DIABETES MELLITUS, AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE OR CARDIOVASCULAR DISEASE Stichting Amsterdam UMC (NL) 2026-01-07 EP claimed
CN-119517408-A Method for establishing death prediction model of new-onset type 2 diabetes and application 中南大学湘雅二医院 2025-02-25 CN claimed
US-20240368831-A1 PROCESS FOR DYEING TEXTILES SANKO TEKSTIL ISLETMELERI SAN. VE TIC. A.S. 2024-11-07 US claimed
WO-2024130198-A9 NOVEL TRYPTOPHANASES FROM STREPTOMYCES WITH NOVEL PROPERTIES AND THE USES THEREOF CONAGEN INC. (US) 2024-08-22 WO claimed
WO-2024130198-A2 NOVEL TRYPTOPHANASES FROM STREPTOMYCES WITH NOVEL PROPERTIES AND THE USES THEREOF CONAGEN INC. (US) 2024-06-20 WO claimed
CN-118207197-A Immobilization of thermophilic archaea tryptophan synthase on magnetic bead-T4 phage capsid composite carrier 江苏海洋大学 2024-06-18 CN claimed
CN-114222841-B Textile dyeing process 尚科纺织企业工业及贸易公司 2024-04-12 CN claimed
CN-117625504-A Engineering bacterium combined into 6,6' -dibromo indigo as well as preparation method and application thereof 南京合谷生命生物科技有限公司 2024-03-01 CN claimed
CN-116836959-A Enzyme composition for synthesizing neomycin derivative and application thereof 山东大学 2023-10-03 CN claimed
US-20030170222-A1 Beta-superfamily conotoxins UNIVERSITY OF UTAH RESEARCH FOUNDATION 2003-09-11 US claimed
US-20020173449-A1 O-superfamily conotoxin peptides UTAH RESEARCH FOUNDATION, UNIVERSITY OF 2002-11-21 US claimed
EP-1246635-A1 O-SUPERFAMILY CONOTOXIN PEPTIDES University of Utah Research Foundation (US) 2002-10-09 EP claimed
WO-2002060923-A2 B-SUPERFAMILY CONOTOXINS COGNETIX, INC. (US) 2002-08-08 WO claimed
EP-1219603-A2 Tryptophan analogs in proteins, peptides and peptidic structures Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2002-07-03 EP claimed
WO-2001049312-A2 O-SUPERFAMILY CONOTOXIN PEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2001-07-12 WO claimed
EP-1039923-A1 GAMMA-CONOPEPTIDES University of Utah Research Foundation (US) 2000-10-04 EP claimed
WO-1999030732-A1 GAMMA-CONOPEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1999-06-24 WO claimed
US-5889147-A OLIGOPEPTIDE, POLYPEPTIDE FROM VENOM OF A CONE SNAIL UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1999-03-30 US claimed
WO-1998031705-A1 BROMO-TRYPTOPHAN CONOPEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-07-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022515-A2 PROCESS FOR DYEING TEXTILES TDO2, TPH2, IDO2 KMT2A 693/4885KDM4E 522/4885MAPT 2931/4885
US-20030170222-A1 Beta-superfamily conotoxins KCNN4, KCNA2, KCNA1 KMT2A 4088/4885KDM4E 4354/4885MAPT 3647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.