⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669277 | 0.91 | PLK1 (0.30) | — | |
| SCHEMBL2644501 | 0.79 | RXRA (0.33) | — | |
| SCHEMBL2669408 | 0.74 | GCK (0.34) | — | |
| SCHEMBL9071944 | 0.74 | GCK (0.34) | — | |
| SCHEMBL642510 | 0.73 | GCK (0.43) | — | |
| SCHEMBL2669399 | 0.72 | GCK (0.36) | — | |
| SCHEMBL2644805 | 0.69 | XDH (0.34) | — | |
| SCHEMBL2669407 | 0.68 | HSP90AB1 (0.31) | — | |
| SCHEMBL2669373 | 0.66 | IRAK4 (0.36) | — | |
| SCHEMBL2669379 | 0.65 | GCK (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122482-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2007-11-01 | — | — | WO | disclosed |