Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | SLC26A4 | O43511 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26693543 | 0.81 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL6976339 | 0.81 | CASP3 (0.62) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470655 | 0.80 | CASP3 (0.84) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713158 | 0.80 | CASP3 (0.84) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL5746156 | 0.79 | CASP3 (0.63) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL26693545 | 0.79 | CASP3 (0.63) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL4124805 | 0.79 | CASP3 (1.00) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470563 | 0.79 | CASP3 (0.77) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470537 | 0.78 | CASP3 (0.80) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470816 | 0.78 | CASP3 (0.80) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346583-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | UNIV LEUVEN KATH (BE) | 2025-11-13 | — | — | US | disclosed |
| EP-4532012-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023227696-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023227696-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346583-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | TRPM4, TRPM2, TRPM6 | CASP3 572/4885SENP8 2867/4885SENP7 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.