Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | SLC26A4 | O43511 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26693543 | 0.85 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL6976339 | 0.85 | CASP3 (0.62) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL30659929 | 0.82 | CASP3 (0.60) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL26693504 | 0.82 | CASP3 (0.60) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL26693510 | 0.81 | CASP3 (0.59) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL26693529 | 0.79 | CASP3 (0.65) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470655 | 0.79 | CASP3 (0.84) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29958563 | 0.79 | L3MBTL1 (0.65) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713158 | 0.79 | CASP3 (0.84) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL724161 | 0.79 | L3MBTL1 (0.65) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651631-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012288-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC (US) | 2005-02-10 | — | — | WO | disclosed |