Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669466 | 0.81 | ALDH1A1 (0.54) | MAOBIDO1 | |
| SCHEMBL18769636 | 0.79 | HDAC1 (0.55) | MAOBIDO1HDAC1ACHE | |
| SCHEMBL27666007 | 0.79 | IDO1 (0.53) | MAOBIDO1MAOATACR1 | |
| SCHEMBL2094372 | 0.79 | IDO1 (0.53) | MAOBIDO1MAOATACR1 | |
| SCHEMBL7505411 | 0.79 | HDAC1 (0.54) | MAOBIDO1MAOAHDAC1 | |
| SCHEMBL9072520 | 0.78 | IDO1 (0.47) | MAOBIDO1MAOAFFAR4 | |
| SCHEMBL2669347 | 0.78 | MAOB (0.43) | MAOBHDAC1HDAC2ACHE | |
| SCHEMBL3233422 | 0.77 | MAOB (0.50) | MAOBIDO1MAOAHDAC1 | |
| SCHEMBL3088642 | 0.76 | IDO1 (0.70) | MAOBIDO1MAOATACR1 | |
| SCHEMBL6902273 | 0.75 | IDO1 (0.61) | MAOBIDO1MAOAFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084044-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2008-07-17 | — | — | WO | disclosed |