Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166473 | 0.83 | THRA (0.49) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9072520 | 0.81 | IDO1 (0.47) | MAOBSLC1A5POLBL3MBTL1 | |
| SCHEMBL2669466 | 0.81 | ALDH1A1 (0.54) | MAOBALDH1A1 | |
| SCHEMBL4846056 | 0.80 | CHRM3 (0.44) | MAOBKDM4ECHRM3ALDH1A1TAAR1 | |
| SCHEMBL6928724 | 0.80 | MAOB (0.47) | MAOBKDM4ETHRATHRBSLC1A5 | |
| SCHEMBL24674904 | 0.79 | TSHR (0.40) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3079544 | 0.78 | CHRM3 (0.45) | MAOBKDM4ETHRATHRBCHRM3 | |
| SCHEMBL6237592 | 0.78 | MAOB (0.40) | MAOBKDM4ESLC1A5CHRM3ALDH1A1 | |
| SCHEMBL2668500 | 0.78 | KCNH2 (0.46) | KDM4EALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL2669460 | 0.78 | MAOB (0.52) | MAOBHDAC1HDAC2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084044-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2008-07-17 | — | — | WO | disclosed |