Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26695699 | 0.81 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2MEN1TP53 | |
| SCHEMBL27440444 | 0.79 | LMNA (0.44) | LMNAKMT2ASMN1; SMN2MEN1TP53 | |
| SCHEMBL29998765 | 0.78 | LMNA (0.51) | LMNAKMT2ASMN1; SMN2MEN1USP2 | |
| SCHEMBL4509698 | 0.75 | LMNA (0.73) | LMNAKMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL27449378 | 0.74 | SUV39H2 (0.53) | LMNA | |
| SCHEMBL16035866 | 0.72 | CYP1A2 (0.56) | KMT2ASMN1; SMN2MEN1TP53KDM4E | |
| SCHEMBL4496926 | 0.71 | LMNA (0.57) | LMNAKMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL17310093 | 0.71 | SUV39H2 (0.49) | LMNAKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL1592123 | 0.70 | LMNA (0.56) | LMNAKMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL901378 | 0.70 | LMNA (0.66) | LMNAKMT2ASMN1; SMN2MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023222115-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |