Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775467 | 0.81 | LMNA (0.64) | LMNASMN1; SMN2CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL26695772 | 0.81 | LMNA (0.60) | LMNAIKBKBSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL26695651 | 0.80 | SPHK1 (0.42) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27440444 | 0.79 | LMNA (0.44) | LMNASMN1; SMN2CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29998765 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27449378 | 0.74 | SUV39H2 (0.53) | LMNA | |
| SCHEMBL29283185 | 0.74 | LMNA (0.41) | LMNAHRH3 | |
| SCHEMBL21777093 | 0.74 | CYP1A2 (0.40) | LMNAHRH3SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL26695734 | 0.73 | KDM1A (0.49) | — | |
| SCHEMBL3711790 | 0.72 | LMNA (0.50) | LMNAHRH3IKBKBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023222115-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| CN-117062813-A | Polycyclic compound and application thereof | 四川汇宇制药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |