Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696355 | 0.87 | DYRK1A (0.42) | DYRK1AGSK3BNFATC1MAPTPDPK1 | |
| SCHEMBL26696388 | 0.87 | DYRK1A (0.42) | DYRK1AGSK3BNFATC1MAPTGUSB | |
| SCHEMBL26696325 | 0.87 | GUSB (0.52) | DYRK1AGSK3BNFATC1MAPTGUSB | |
| SCHEMBL4266740 | 0.87 | MAPT (0.48) | DYRK1AGSK3BNFATC1MAPTPDPK1 | |
| SCHEMBL26696364 | 0.81 | CA12 (0.39) | CYP19A1DYRK1AGSK3BNFATC1MAPT | |
| SCHEMBL26696337 | 0.78 | DYRK1A (0.43) | CYP3A4DYRK1AGSK3BNFATC1MAPT | |
| SCHEMBL26696378 | 0.77 | MGAM (0.44) | DYRK1AGSK3BNFATC1MAPTGUSB | |
| SCHEMBL12491378 | 0.76 | DYRK1A (0.49) | DYRK1AGSK3BNFATC1MAPTPDPK1 | |
| SCHEMBL26696352 | 0.76 | GUSB (0.40) | CYP17A1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1992184 | 0.74 | MAPT (0.61) | CYP3A4MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF THE WEST INDIES (TT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | CFTR, CCL11, CEL | CYP17A1 146/4885CYP3A4 720/4885CYP19A1 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.