Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30770199 | 1.00 | PARP1 (0.44) | PARP1PARP2DDB1CRBNOPRL1 | |
| SCHEMBL2986176 | 0.86 | DDB1 (0.54) | PARP1PARP2DDB1CRBNPRKCG | |
| Hydrochloric Acid SCHEMBL2858713 | 0.84 | DDB1 (0.52) | PARP1PARP2DDB1CRBNPRKCG | |
| SCHEMBL26698037 | 0.81 | OPRM1 (0.37) | PARP1PARP2OPRM1MEN1KMT2A | |
| SCHEMBL26698035 | 0.81 | OPRM1 (0.37) | PARP1PARP2OPRM1MEN1KMT2A | |
| SCHEMBL26698016 | 0.81 | DRD2 (0.45) | OPRM1HTR2CLMNAHTR2AKDM4E | |
| SCHEMBL26671825 | 0.81 | CCR3 (0.44) | PARP1PARP2OPRL1OPRM1HTR6 | |
| SCHEMBL26698022 | 0.81 | OPRM1 (0.37) | PARP1PARP2OPRM1MEN1KMT2A | |
| SCHEMBL26698009 | 0.81 | DRD2 (0.51) | PARP1PARP2OPRM1OPRK1HTR2C | |
| SCHEMBL24478396 | 0.80 | TP53 (0.46) | PARP1PARP2DDB1CRBNOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229375-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |
| WO-2023229375-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |