Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HPD | P32754 | 3/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | PRKDC | P78527 | 4/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | LITAF | Q99732 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698009 | 0.95 | DRD2 (0.51) | DRD2SLC6A4HTR1AADRA2AHTR2A | |
| SCHEMBL4712560 | 0.88 | DRD2 (0.58) | DRD2SLC6A4HTR1AADRA2AHTR2A | |
| SCHEMBL26698035 | 0.84 | OPRM1 (0.37) | HPDPIK3CAPRKDCMTORPLD1 | |
| SCHEMBL26698037 | 0.84 | OPRM1 (0.37) | HPDPIK3CAPRKDCMTORPLD1 | |
| SCHEMBL11847280 | 0.82 | DRD2 (0.65) | DRD2SLC6A4HTR1AADRA2AHTR2A | |
| SCHEMBL26697994 | 0.81 | PARP1 (0.44) | HTR2AHTR2CLMNAKDM4EALDH1A1 | |
| SCHEMBL30770199 | 0.81 | PARP1 (0.44) | HTR2AHTR2CLMNAKDM4EALDH1A1 | |
| SCHEMBL26698022 | 0.78 | OPRM1 (0.37) | DRD2SLC6A4HPDPIK3CAPRKDC | |
| SCHEMBL26671825 | 0.78 | CCR3 (0.44) | DRD2SLC6A4PIK3CAMTORHTR6 | |
| SCHEMBL24478284 | 0.78 | HSD17B10 (0.50) | HSD11B1PIK3CAPRKDCMTORTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229375-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |