Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852346 | 1.00 | ACHE (0.44) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL22031512 | 0.82 | KMT2A (0.43) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL27832542 | 0.81 | MAPT (0.50) | KMT2AMAPT | |
| SCHEMBL27689512 | 0.81 | POLB (0.46) | HCAR2KDM4E | |
| SCHEMBL22556883 | 0.81 | KMT2A (0.42) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL12736324 | 0.79 | LMNA (0.53) | ACHEATMHCAR2ELANEKDM4E | |
| SCHEMBL6943160 | 0.79 | KMT2A (0.50) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL12735751 | 0.78 | ATM (0.46) | KMT2AATMHCAR2GCK | |
| SCHEMBL27673606 | 0.78 | CYP19A1 (0.55) | KMT2ASMN1; SMN2ATMRECQLALDH1A1 | |
| Hydrochloric Acid SCHEMBL29119748 | 0.76 | ATM (0.44) | KMT2AATMHCAR2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |