Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.52 |
| ▸ | CHRNG | P07510 | 1/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | CHRND | Q07001 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776118 | 0.86 | KDM2B (0.51) | KDM2BALDH1A1TSHRCHRNA1CHRNG | |
| SCHEMBL27265700 | 0.81 | CNR2 (0.48) | ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL25980654 | 0.81 | CNR2 (0.48) | ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL18360283 | 0.81 | KDM2B (0.62) | KDM2BALDH1A1NPC1LMNARAB9A | |
| SCHEMBL8222788 | 0.81 | USP30 (0.53) | KDM2BALDH1A1TSHRCHRNA1CHRNG | |
| SCHEMBL25980703 | 0.80 | CNR2 (0.47) | ALDH1A1CHRNB2CHRNA4KMT2AGAA | |
| SCHEMBL5210032 | 0.79 | MGLL (0.62) | KDM2BALDH1A1CES2CES1MEN1 | |
| SCHEMBL30771226 | 0.79 | MGLL (0.62) | KDM2BALDH1A1CES2CES1MEN1 | |
| SCHEMBL14646983 | 0.78 | KDM2B (0.57) | KDM2BALDH1A1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL7309424 | 0.78 | CES2 (0.65) | KDM2BNPC1RAB9ASMN1; SMN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |