Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNG | P07510 | 1/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | CHRND | Q07001 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698259 | 0.86 | KDM2B (0.57) | KDM2BCHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL8222788 | 0.85 | USP30 (0.53) | KDM2BCHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL20482125 | 0.84 | KDM2B (0.52) | KDM2BALDH1A1HCRTR1HCRTR2MEN1 | |
| SCHEMBL20482103 | 0.84 | KDM2B (0.52) | KDM2BALDH1A1HCRTR1HCRTR2MEN1 | |
| SCHEMBL4780546 | 0.83 | CNR2 (0.41) | KDM2BALDH1A1TSHR | |
| SCHEMBL4725359 | 0.82 | DRD2 (0.42) | KDM2B | |
| SCHEMBL4776003 | 0.82 | MGLL (0.48) | ALDH1A1MGLL | |
| SCHEMBL3088285 | 0.81 | MCL1 (0.46) | ALDH1A1 | |
| SCHEMBL5172182 | 0.81 | MCL1 (0.46) | ALDH1A1 | |
| SCHEMBL3518713 | 0.81 | HPGD (0.51) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |