Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26434787 | 0.86 | MRGPRX4 (0.58) | MRGPRX4MAPTL3MBTL1LMNAHTT | |
| SCHEMBL15588794 | 0.83 | MRGPRX4 (0.56) | MRGPRX4MAPTLMNAHTTFFAR1 | |
| SCHEMBL171841 | 0.83 | MRGPRX4 (0.68) | MRGPRX4MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL22114129 | 0.81 | TUBB1 (0.52) | MRGPRX4LMNA | |
| SCHEMBL16210864 | 0.80 | MRGPRX4 (0.53) | MRGPRX4MAPTL3MBTL1LMNAHTT | |
| SCHEMBL257777 | 0.80 | MRGPRX4 (0.57) | MRGPRX4LMNAHTTFFAR1RXRA | |
| SCHEMBL19703006 | 0.78 | MRGPRX4 (0.45) | MRGPRX4MAPTTDP1LMNAHTT | |
| SCHEMBL19374625 | 0.76 | MRGPRX4 (0.50) | MRGPRX4MAPTMAPK1MAOBRECQL | |
| SCHEMBL16210297 | 0.76 | MRGPRX4 (0.53) | MRGPRX4MAPTLMNAHTTS1PR5 | |
| SCHEMBL13905218 | 0.76 | MRGPRX4 (0.48) | MRGPRX4MAPTTDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023232753-A1 | FERROELECTRIC SMECTIC LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-12-07 | — | — | WO | disclosed |
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |