Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588794 | 0.93 | MRGPRX4 (0.56) | MRGPRX4NPC1RAB9AMAPTLMNA | |
| SCHEMBL16210864 | 0.90 | MRGPRX4 (0.53) | MRGPRX4NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL171841 | 0.89 | MRGPRX4 (0.68) | MRGPRX4MAPTMAOBFFAR4SMN1; SMN2 | |
| SCHEMBL257777 | 0.86 | MRGPRX4 (0.57) | MRGPRX4LMNAFFAR4PTGER1HTT | |
| SCHEMBL19374625 | 0.86 | MRGPRX4 (0.50) | MRGPRX4RAB9ARECQLMAPTALDH1A1 | |
| SCHEMBL16210297 | 0.86 | MRGPRX4 (0.53) | MRGPRX4NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL26698908 | 0.86 | MRGPRX4 (0.56) | MRGPRX4NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL16838745 | 0.82 | MAOA (0.57) | MRGPRX4CYP1A2CYP2C19MAPTLMNA | |
| SCHEMBL12908047 | 0.81 | MAPT (0.52) | MRGPRX4NPC1RAB9AMAPTLMNA | |
| SCHEMBL17854923 | 0.81 | MRGPRX4 (0.55) | MRGPRX4NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066826-A1 | ELECTRO-MECHANICAL CONVERTERS USING FERROELECTRIC NEMATIC MATERIAL | MERCK PATENT GMBH (DE) | 2023-04-27 | — | — | WO | disclosed |