Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611368 | 0.86 | KDM4E (0.40) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL26698645 | 0.81 | CYP2C19 (0.42) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL26699228 | 0.81 | KDM4E (0.54) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL26611226 | 0.71 | KDM4E (0.40) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL26611035 | 0.69 | KDM4E (0.48) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL26698621 | 0.67 | CYP2C19 (0.48) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL31716266 | 0.67 | KDM4E (0.40) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL26612297 | 0.67 | KDM4E (0.62) | KDM4EPOLBMAPTPKMSMN1; SMN2 | |
| SCHEMBL26699477 | 0.64 | KDM4E (0.49) | KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL26611002 | 0.64 | PTGS2 (0.36) | KDM4EPOLBMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023203174-A1 | HETEROCYCLIC CULLIN RING UBIQUITIN LIGASE COMPOUNDS AND USES THEREOF | PROXYGEN GMBH (AT) | 2023-10-26 | — | — | WO | disclosed |