Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719021 | 0.90 | GCG (0.43) | ADRB2ADRB1ADRB3LMNAL3MBTL1 | |
| SCHEMBL718011 | 0.87 | MAPT (0.42) | ADRB2ADRB1ADRB3LMNAL3MBTL1 | |
| SCHEMBL720711 | 0.86 | CA12 (0.49) | LMNAL3MBTL1HTTKDM4EMAPT | |
| SCHEMBL719499 | 0.84 | MAPT (0.45) | ADRB2ADRB1ADRB3LMNAL3MBTL1 | |
| SCHEMBL721127 | 0.79 | RAB9A (0.39) | LMNAL3MBTL1HTTKDM4EMAPT | |
| SCHEMBL720851 | 0.76 | GCG (0.54) | NPC1RAB9A | |
| SCHEMBL3407767 | 0.76 | LMNA (0.45) | LMNAL3MBTL1HTTKDM4EMAPT | |
| SCHEMBL719600 | 0.75 | MAPT (0.38) | LMNAL3MBTL1HTTMAPTTDP1 | |
| SCHEMBL2669825 | 0.75 | NPC1 (0.46) | LMNAL3MBTL1KDM4EMAPTGAA | |
| SCHEMBL716401 | 0.74 | GCG (0.37) | LMNAL3MBTL1HTTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |