Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GCG | P01275 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719021 | 0.85 | GCG (0.43) | LMNAL3MBTL1KDM4EHTTMAPT | |
| SCHEMBL718011 | 0.77 | MAPT (0.42) | LMNAL3MBTL1KDM4EHTTMAPT | |
| SCHEMBL719589 | 0.76 | NPC1 (0.48) | L3MBTL1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL718772 | 0.76 | GCG (0.44) | L3MBTL1KDM4ENPC1RAB9AGCG | |
| SCHEMBL3400803 | 0.76 | NPC1 (0.47) | L3MBTL1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL2669949 | 0.76 | ADRB2 (0.44) | LMNAL3MBTL1KDM4EHTTMAPT | |
| SCHEMBL720711 | 0.75 | CA12 (0.49) | LMNAL3MBTL1KDM4EHTTMAPT | |
| SCHEMBL721127 | 0.74 | RAB9A (0.39) | LMNAL3MBTL1KDM4EHTTMAPT | |
| SCHEMBL719499 | 0.73 | MAPT (0.45) | LMNAL3MBTL1KDM4EMAPTNPC1 | |
| SCHEMBL716401 | 0.70 | GCG (0.37) | LMNAL3MBTL1HTTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |