Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669893 | 0.86 | PRSS1 (0.35) | RAB9ANPC1P2RY12 | |
| SCHEMBL2669939 | 0.85 | NPC1 (0.39) | RAB9ANPC1 | |
| SCHEMBL2669958 | 0.85 | CASP3 (0.39) | RAB9ANPC1CASP3SENP7 | |
| SCHEMBL2669836 | 0.85 | NPC1 (0.33) | RAB9ANPC1TDP1 | |
| SCHEMBL9070786 | 0.84 | NPC1 (0.37) | RAB9ANPC1 | |
| SCHEMBL720067 | 0.84 | TDP1 (0.43) | RAB9ANPC1TDP1SMN1; SMN2LMNA | |
| SCHEMBL2669954 | 0.84 | L3MBTL1 (0.34) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2669842 | 0.84 | NPC1 (0.33) | RAB9ANPC1 | |
| SCHEMBL2669819 | 0.83 | CYP4F2 (0.36) | RAB9ANPC1MAPT | |
| SCHEMBL2669955 | 0.83 | ESR1 (0.39) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |