Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.35 |
| ▸ | F7 | P08709 | 4/20 | 0.35 |
| ▸ | F3 | P13726 | 4/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669954 | 0.93 | L3MBTL1 (0.34) | L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL2669903 | 0.92 | L3MBTL1 (0.34) | L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL718399 | 0.92 | PRSS1 (0.37) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL720836 | 0.86 | PRSS1 (0.37) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL2669952 | 0.86 | RAB9A (0.41) | P2RY12NPC1RAB9A | |
| SCHEMBL2669958 | 0.85 | CASP3 (0.39) | L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL2669939 | 0.85 | NPC1 (0.39) | PDE4ANPC1RAB9A | |
| SCHEMBL2669842 | 0.85 | NPC1 (0.33) | PDE4AKMT2ANPC1RAB9A | |
| SCHEMBL2669898 | 0.84 | MAPT (0.38) | L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL721354 | 0.84 | KMT2A (0.36) | L3MBTL1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |