Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | KLK7 | P49862 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26699433 | 0.84 | TSHR (0.46) | FPR2ACACBEPHX2CTSCPPARG | |
| SCHEMBL26698133 | 0.75 | PPARG (0.44) | NOS2FPR2ACACBPPARGPPARA | |
| SCHEMBL6575200 | 0.75 | FPR2 (0.49) | NOS2FPR2ACACBEPHX2PPARG | |
| SCHEMBL13572956 | 0.75 | FPR2 (0.49) | NOS2FPR2ACACBEPHX2PPARG | |
| SCHEMBL7597924 | 0.75 | FPR2 (0.49) | NOS2FPR2ACACBEPHX2PPARG | |
| SCHEMBL26697684 | 0.74 | SLC6A2 (0.42) | FPR2ACACBEPHX2CTSCPPARG | |
| SCHEMBL15446245 | 0.74 | PPARG (0.50) | NOS2ACACBPPARGPPARA | |
| SCHEMBL26700528 | 0.74 | GAA (0.40) | NOS2FPR2ACACBCTSCPPARG | |
| SCHEMBL15180970 | 0.73 | PTPRB (0.58) | NOS2FPR2ACACBPPARGPPARA | |
| SCHEMBL21129084 | 0.72 | CYP1A2 (0.56) | PPARGPPARAKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269400-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Molecure SA (PL) | 2023-11-01 | — | — | EP | disclosed |