Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26699754 | 0.76 | CTSC (0.38) | ACACBFPR2PPARGPPARACA1 | |
| SCHEMBL26699433 | 0.74 | TSHR (0.46) | GAAACACBFPR2PPARGPPARA | |
| SCHEMBL26699700 | 0.74 | NOS2 (0.45) | ACACBFPR2PPARGPPARACTSC | |
| SCHEMBL12942876 | 0.73 | SLC6A2 (0.52) | ACACBHPGDHSD17B10PPARGPPARA | |
| SCHEMBL7622290 | 0.71 | EPHX2 (0.38) | ACACBHPGDFPR2PPARGPPARA | |
| SCHEMBL8481611 | 0.69 | FPR2 (0.41) | ACACBFPR2PPARGPPARAPSMB5 | |
| SCHEMBL5036248 | 0.69 | ACACB (0.51) | ACACBHPGDHSD17B10FPR2PSMB5 | |
| SCHEMBL5036948 | 0.69 | ACACB (0.51) | ACACBHPGDHSD17B10FPR2PSMB5 | |
| SCHEMBL7615213 | 0.67 | MME (0.46) | ACACBPPARGPPARACA2PSMB5 | |
| SCHEMBL7622306 | 0.67 | PPARG (0.38) | GAAACACBHPGDHSD17B10FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269400-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Molecure SA (PL) | 2023-11-01 | — | — | EP | disclosed |