Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669921 | 0.85 | GCG (0.41) | GCGHDAC6NQO1NAMPTBRD4 | |
| SCHEMBL2669988 | 0.85 | GCGR (0.43) | GCGEYA3SLC22A12 | |
| SCHEMBL720542 | 0.80 | CYP2C19 (0.37) | GCGCYP2C19HDAC6EYA3SLC22A12 | |
| SCHEMBL2669773 | 0.78 | NPC1 (0.39) | GCGHDAC6MEN1KMT2ANPSR1 | |
| SCHEMBL720005 | 0.77 | CYP2C19 (0.35) | GCGCYP2C19HDAC6EYA3SLC22A12 | |
| SCHEMBL2669883 | 0.75 | GCG (0.44) | GCGHDAC6MEN1KMT2ANAMPT | |
| SCHEMBL9070785 | 0.74 | GCG (0.43) | GCGCYP2C19HDAC6CYP2C9NAMPT | |
| SCHEMBL719015 | 0.72 | GCG (0.41) | GCGCYP2C19HDAC6MEN1LMNA | |
| SCHEMBL720006 | 0.71 | TP53 (0.34) | CYP2C19HDAC6EYA3SLC22A12CYP2C9 | |
| SCHEMBL2669986 | 0.71 | GCG (0.40) | GCGHDAC6NAMPTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |