Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 5/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070785 | 0.90 | GCG (0.43) | GCGNAMPTMCHR1TNFPARP1 | |
| SCHEMBL2669986 | 0.86 | GCG (0.40) | GCGNAMPTMCHR1TNFPARP1 | |
| SCHEMBL719715 | 0.79 | HTR3A (0.37) | GCGNAMPTMCHR1HDAC6KAT2B | |
| SCHEMBL2669921 | 0.76 | GCG (0.41) | GCGNAMPTMCHR1HDAC6HTT | |
| SCHEMBL2669985 | 0.76 | GCGR (0.47) | GCG | |
| SCHEMBL721466 | 0.76 | PDE7A (0.36) | GCGNAMPTKAT2BSSTR4ALDH1A1 | |
| SCHEMBL2669983 | 0.75 | GCG (0.41) | GCGNAMPTMCHR1HDAC6MEN1 | |
| SCHEMBL2669773 | 0.70 | NPC1 (0.39) | GCGHDAC6ALDH1A1MEN1HPGD | |
| SCHEMBL721467 | 0.70 | SSTR4 (0.35) | NAMPTTNFHDAC6KAT2BSSTR4 | |
| SCHEMBL720161 | 0.70 | P2RX7 (0.38) | GCGNAMPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |