Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729562 | 0.82 | ALDH1A1 (0.38) | DNM1ALDH1A1 | |
| SCHEMBL26707321 | 0.82 | ALDH1A1 (0.38) | DNM1ALDH1A1 | |
| SCHEMBL25090005 | 0.81 | DNM1 (0.34) | DNM1ALDH1A1 | |
| SCHEMBL26700632 | 0.80 | LGALS1 (0.35) | ALDH1A1 | |
| SCHEMBL15160684 | 0.80 | SMN1; SMN2 (0.42) | DNM1ALDH1A1 | |
| SCHEMBL26707317 | 0.79 | — | — | |
| SCHEMBL23729600 | 0.78 | MEN1 (0.44) | — | |
| SCHEMBL18458463 | 0.77 | CAPN1 (0.34) | DNM1ALDH1A1 | |
| SCHEMBL24941942 | 0.76 | LGALS1 (0.36) | DNM1ALDH1A1 | |
| SCHEMBL24459020 | 0.76 | KMT2A (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, BRCA1 | DNM1 2218/4885ALDH1A1 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.