Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26703992 | 0.89 | LMNA (0.67) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL26703989 | 0.88 | LMNA (0.77) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL11626193 | 0.87 | SORT1 (0.65) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL4181950 | 0.87 | LMNA (0.70) | LMNANPC1RAB9APOLBKMT2A | |
| Hydrochloric Acid SCHEMBL11626061 | 0.86 | SORT1 (0.64) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL26704026 | 0.84 | RAB9A (0.63) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL26704199 | 0.84 | KMT2A (0.57) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL14082655 | 0.83 | LMNA (0.62) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL26704104 | 0.82 | RAB9A (0.61) | LMNANPC1RAB9APOLBKMT2A | |
| SCHEMBL23795935 | 0.82 | LMNA (0.58) | LMNANPC1RAB9APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211195-A1 | N-OXIDE COMPOUNDS AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-11-02 | — | — | WO | disclosed |