Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313114 | 0.88 | ANO1 (0.37) | ANO1MAPTTP53SMN1; SMN2ANO2 | |
| SCHEMBL29376104 | 0.86 | L3MBTL1 (0.40) | ANO1MAPTTP53SMN1; SMN2ANO2 | |
| SCHEMBL22463090 | 0.86 | L3MBTL1 (0.40) | ANO1MAPTTP53SMN1; SMN2ANO2 | |
| SCHEMBL22463091 | 0.85 | ANO1 (0.36) | ANO1MAPTTP53SMN1; SMN2ANO2 | |
| SCHEMBL7653960 | 0.82 | BAZ2B (0.42) | MAPTTP53RXRARXRBRXRG | |
| SCHEMBL22463108 | 0.81 | AR (0.41) | ANO1MAPTADRA2APDK1PDK2 | |
| SCHEMBL22463112 | 0.79 | ELANE (0.36) | ANO1MAPTTP53SMN1; SMN2ANO2 | |
| SCHEMBL22463113 | 0.79 | ELANE (0.36) | ANO1MAPTTP53SMN1; SMN2ANO2 | |
| SCHEMBL18992141 | 0.76 | JAK2 (0.42) | ANO1MAPTTP53ADRA2AALDH1A1 | |
| SCHEMBL24320587 | 0.74 | HLA-DRB1 (0.36) | SMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239894-A1 | THERAPEUTIC BINDING MOLECULES | MEDIMMUNE LIMITED (GB) | 2024-07-18 | — | — | US | disclosed |
| US-11795225-B2 | Therapeutic binding molecules | MEDIMMUNE LIMITED (GB) | 2023-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795225-B2 | Therapeutic binding molecules | EPCAM, IGSF11, FCGR3B | ANO1 4155/4885MAPT 1237/4885TP53 199/4885 |
| US-20240239894-A1 | THERAPEUTIC BINDING MOLECULES | EPCAM, IGSF11, FCGR3B | ANO1 4155/4885MAPT 1237/4885TP53 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.