Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 10/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388915 | 0.89 | TLR8 (0.73) | NOTUMALDH1A1TLR8TSHRNPC1 | |
| SCHEMBL17694561 | 0.89 | NOTUM (0.78) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL2610163 | 0.86 | NOTUM (0.75) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL5571187 | 0.78 | NOTUM (0.91) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL3685411 | 0.78 | NOTUM (0.64) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL1194538 | 0.78 | NOTUM (0.64) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL14814390 | 0.78 | NOTUM (1.00) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL3537328 | 0.78 | NOTUM (1.00) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL19356867 | 0.78 | NOTUM (0.64) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL9096052 | 0.78 | NOTUM (0.64) | NOTUMKDM4EALDH1A1LMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006712-B1 | HETEROCYCLIC DERIVATIVES OF (4-ARYLOXYMETHYL-1.3-DIOXOLAN-2-YL) METHYL-1H-IMIDAZOLES AND -1H-1.2.4-TRIAZOLES, THEIR PREPARATION AND THE DERIVATIVES FOR USE AS FUNGICIDES AND BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-11-30 | — | — | EP | claimed |
| EP-0006712-A1 | Heterocyclic derivatives of (4-aryloxymethyl-1.3-dioxolan-2-yl) methyl-1H-imidazoles and -1H-1.2.4-triazoles, their preparation and the derivatives for use as fungicides and bactericides | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | claimed |
| EP-3135669-B1 | OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME | DONG A ST CO LTD (KR) | 2024-08-28 | — | — | EP | disclosed |
| US-20230192733-A1 | SUBSTITUTED PHENYL ET458HYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE | 2023-06-22 | — | — | US | disclosed |
| US-9809583-B2 | Oxazolidine-based compound and selective androgen receptor agonist comprising same | DONG-A ST CO., LTD. (KR) | 2017-11-07 | — | — | US | disclosed |
| CN-106978193-A | Flexure type liquid-crystal compounds and its synthetic method | 华东理工大学 | 2017-07-25 | — | — | CN | disclosed |
| EP-3135669-A1 | OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME | Dong-A ST Co., Ltd. (KR) | 2017-03-01 | — | — | EP | disclosed |
| US-20170050955-A1 | OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME | DONG-A ST CO., LTD. (KR) | 2017-02-23 | — | — | US | disclosed |
| US-9149465-B2 | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| WO-2013059582-A2 | SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES | NUPOTENTIAL, INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| US-20120289540-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2012-11-15 | — | — | US | disclosed |
| EP-0034276-B1 | PHENYLPIPERAZINE DERIVATIVES OF 1,3,4-OXADIAZOLYL PHENOLS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1983-11-09 | — | — | EP | disclosed |
| US-4353904-A | TREATMENT OF HYPERTONIA | BASF AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4353904-A | TREATMENT OF HYPERTONIA | BASF AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4353904-A | TREATMENT OF HYPERTONIA | BASF AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0056866-A2 | Phenylpiperazine derivatives of heterylphenols and hetarylanilines, their preparation and their pharmaceutical compositions | BASF Aktiengesellschaft (DE) | 1982-08-04 | — | — | EP | disclosed |
| US-4313953-A | BACTERICIDES, FUNGICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-02-02 | — | — | US | disclosed |
| EP-0034276-A2 | Phenylpiperazine derivatives of 1,3,4-oxadiazolyl phenols, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-08-26 | — | — | EP | disclosed |
| US-4218458-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1980-08-19 | — | — | US | disclosed |
| EP-0006712-A1 | Heterocyclic derivatives of (4-aryloxymethyl-1.3-dioxolan-2-yl) methyl-1H-imidazoles and -1H-1.2.4-triazoles, their preparation and the derivatives for use as fungicides and bactericides | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289540-A1 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | BRAF, PRKDC, RAF1 | NOTUM 2961/4885KDM4E 2009/4885ALDH1A1 1389/4885 |
| US-20230192733-A1 | SUBSTITUTED PHENYL ET458HYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SARS1, ACE2, ACE | NOTUM 1389/4885KDM4E 100/4885ALDH1A1 4373/4885 |
| US-20170050955-A1 | OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME | AR, SHBG, MUSK | NOTUM 1531/4885KDM4E 1579/4885ALDH1A1 1632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.