Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802500 | 0.71 | NR3C1 (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL23093119 | 0.71 | NR3C1 (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7004578 | 0.65 | KDM4E (1.00) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29746267 | 0.65 | KDM4E (1.00) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL3249226 | 0.63 | RPS6KB2 (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL22824500 | 0.62 | RAB9A (0.65) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7466888 | 0.61 | RAB9A (0.62) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL19455590 | 0.61 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5329732 | 0.60 | RAB9A (0.80) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL16855380 | 0.60 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357099-A1 | PYRAZOLO [3,4-B] PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR | EUROCHEM ANTWERPEN (BE) | 2023-11-09 | — | — | US | disclosed |
| US-20230357099-A1 | PYRAZOLO [3,4-B] PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR | EUROCHEM ANTWERPEN (BE) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357099-A1 | PYRAZOLO [3,4-B] PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR | CBR1, CYC1, CBR3 | ALDH1A1 1065/4885LMNA 4241/4885MAPT 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.