SCHEMBL2671978

SCHEMBL2671978

[CH2]CCc1ccc(N)cc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 3/20 0.39
TSHR P16473 3/20 0.36
MAPT P10636 3/20 0.36
GAA P10253 2/20 0.36
HTT P42858 2/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GFER P55789 1/20 0.33
CYP19A1 P11511 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
CASP7 P55210 1/20 0.33
ATM Q13315 1/20 0.33
CYP3A4 P08684 3/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2567612 0.87 CASP1 (0.37) CASP1TSHRMAPTGAAHTT
SCHEMBL10890416 0.85 CASP1 (0.46) CASP1TSHRMAPTGAAHTT
SCHEMBL14675505 0.85 CASP1 (0.35) CASP1TSHRMAPTGAAHTT
SCHEMBL2671870 0.84 CASP1 (0.34) CASP1TSHRMAPTGAAHTT
SCHEMBL14674256 0.84 CASP1 (0.34) CASP1TSHRMAPTGAAHTT
SCHEMBL28158723 0.82 CASP1 (0.34) CASP1TSHRMAPTGAAHTT
SCHEMBL29377795 0.81 CASP1 (0.42) CASP1TSHRMAPTGAAHTT
SCHEMBL10894932 0.81 CASP1 (0.42) CASP1TSHRMAPTGAAHTT
SCHEMBL126188 0.81 CASP1 (0.42) CASP1TSHRMAPTGAAHTT
SCHEMBL1048211 0.81 CASP1 (0.42) CASP1TSHRMAPTGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115595159-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司(TW) 2023-01-13 CN disclosed
CN-115368914-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 奇美实业股份有限公司 2022-11-22 CN disclosed
CN-115368913-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 奇美实业股份有限公司 2022-11-22 CN disclosed
CN-114507149-A Diamine compound, polymer, alignment agent, alignment film, and liquid crystal display element 奇美实业股份有限公司 2022-05-17 CN disclosed
CN-109085722-B Method for manufacturing liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2022-05-10 CN disclosed
CN-113930248-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2022-01-14 CN disclosed
CN-113930247-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2022-01-14 CN disclosed
CN-113773858-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司 2021-12-10 CN disclosed
CN-109207170-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2021-12-10 CN disclosed
CN-112852446-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2021-05-28 CN disclosed
US-20130004679-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2013-01-03 US disclosed
US-8329823-B2 Photocrosslinkable materials ROLIC AG (CH) 2012-12-11 US disclosed
US-8173749-B2 Photocrosslinkable materials ROLIC AG (CH) 2012-05-08 US disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed
EP-1801097-A1 Photocrosslinkable materials Rolic AG (CH) 2007-06-27 EP disclosed
EP-1797863-A1 Combinations of dye precursors comprising a diaminopyrazole derivative, an m-aminophenol derivative and an m-phenylene diamine derivative HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD CASP1 1292/4885TSHR 3933/4885MAPT 295/4885
US-20130004679-A1 PHOTOCROSSLINKABLE MATERIALS DDC, PARG, ALAD CASP1 1292/4885TSHR 3933/4885MAPT 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.