Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.36 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.35 |
| ▸ | SCN4A known ✓ | P35499 | 1/20 | 0.32 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A known ✓ | Q15858 | 1/20 | 0.32 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442212 | 0.89 | — | — | |
| Sulfuric Acid SCHEMBL11850568 | 0.87 | TRPA1 (0.40) | ALDH1A1TDP1TRPA1CA5ACA5B | |
| Hydrochloric Acid SCHEMBL2672201 | 0.87 | ALDH1A1 (0.42) | NPSR1PAOXALDH1A1TDP1OPRK1 | |
| Acetic Acid SCHEMBL2672332 | 0.84 | ALDH1A1 (0.40) | NPSR1PAOXALDH1A1TDP1OPRK1 | |
| SCHEMBL20067016 | 0.84 | ALDH1A1 (0.44) | PAOXALDH1A1TDP1OPRK1CHRM2 | |
| Sulfuric Acid SCHEMBL78884 | 0.78 | NPSR1 (0.46) | NPSR1PAOXALDH1A1TDP1CHRM2 | |
| Sulfuric Acid SCHEMBL11137355 | 0.78 | NPSR1 (0.46) | NPSR1PAOXALDH1A1TDP1CHRM2 | |
| Sulfuric Acid SCHEMBL29289482 | 0.78 | NPSR1 (0.46) | NPSR1PAOXALDH1A1TDP1CHRM2 | |
| Sulfuric Acid SCHEMBL11137352 | 0.78 | NPSR1 (0.46) | NPSR1PAOXALDH1A1TDP1CHRM2 | |
| Sulfuric Acid SCHEMBL16059228 | 0.78 | NPSR1 (0.46) | NPSR1PAOXALDH1A1TDP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046933-B1 | DETERGENT COMPOSITION | RECKITT BENCKISER NV (NL) | 2015-07-15 | — | — | EP | disclosed |
| US-8173587-B2 | Detergent composition | RECKITT BENCKISER N.V. (NL) | 2012-05-08 | — | — | US | disclosed |
| US-20090325840-A1 | Detergent Composition | RECKITT BENCKISER N.V. (NL) | 2009-12-31 | — | — | US | disclosed |
| EP-2049643-A1 | USE OF AMINOACETONES AND SALTS THEREOF AS BLEACHING BOOSTERS FOR PEROXYGEN COMPOUNDS | Clariant Finance (BVI) Limited (VG) | 2009-04-22 | — | — | EP | disclosed |
| EP-2046933-A1 | DETERGENT COMPOSITION | Reckitt Benckiser N.V. (NL) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008015443-A1 | DETERGENT COMPOSITION | RECKITT BENCKISER N.V. (NL) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008014965-A1 | USE OF AMINOACETONES AND SALTS THEREOF AS BLEACHING BOOSTERS FOR PEROXYGEN COMPOUNDS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2008-02-07 | — | — | WO | disclosed |