Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.60 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.44 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562812 | 1.00 | LPAR1 (0.60) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL10566866 | 1.00 | LPAR1 (0.60) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL753952 | 0.99 | LPAR1 (0.58) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL3274160 | 0.93 | LPAR1 (0.53) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL667267 | 0.93 | LPAR1 (0.53) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL10563457 | 0.91 | LPAR1 (0.53) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| Ammonia Solution, Strong SCHEMBL6373587 | 0.90 | LPAR1 (0.60) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL17291865 | 0.90 | LPAR1 (0.47) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL2538875 | 0.86 | LPAR1 (0.48) | LPAR1LPAR3LPAR2LPAR5USP2 | |
| SCHEMBL7820811 | 0.86 | LPAR3 (0.46) | LPAR1LPAR3LPAR2LPAR5USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8460709-B2 | Pharmaceutical microparticles | NOVARTIS AG (CH) | 2013-06-11 | — | — | US | claimed |
| US-20120107408-A1 | PHARMACEUTICAL MICROPARTICLES | NOVARTIS AG (CH) | 2012-05-03 | — | — | US | claimed |