SCHEMBL753952

SCHEMBL753952

CCCCCOC[C@H](COC(C(O)CO)P(=O)(O)O)OCCCCC

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 9/20 0.58
LPAR3 Q9UBY5 9/20 0.58
LPAR2 Q9HBW0 6/20 0.51
LPAR5 Q9H1C0 6/20 0.46
USP2 O75604 1/20 0.45
LPAR6 P43657 5/20 0.42
LPAR4 Q99677 5/20 0.42
TLR2 O60603 4/20 0.40
SPHK1 Q9NYA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10566866 0.99 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL10562812 0.99 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL2672057 0.99 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL3274160 0.92 LPAR1 (0.53) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL667267 0.92 LPAR1 (0.53) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL17291865 0.91 LPAR1 (0.47) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL10563457 0.90 LPAR1 (0.53) LPAR1LPAR3LPAR2LPAR5USP2
Ammonia Solution, Strong SCHEMBL6373587 0.88 LPAR1 (0.60) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL2538875 0.87 LPAR1 (0.48) LPAR1LPAR3LPAR2LPAR5USP2
SCHEMBL1393763 0.84 MAPT (0.50) LPAR1LPAR3LPAR2LPAR5LPAR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023190176-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE, AND METHOD FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE USING SAME 日油株式会社 2023-10-05 WO claimed
WO-2004087107-A1 CATIONIC LIPOSOME TARGETING SEBACEOUS GLANDS TRICHOGENE INC. (KR) 2004-10-14 WO claimed
WO-2024014512-A1 LYOPHILIZED COMPOSITION OF NUCLEIC-ACID-LOADED LIPID NANOPARTICLES 日油株式会社 2024-01-18 WO disclosed
WO-2023190176-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE, AND METHOD FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE USING SAME 日油株式会社 2023-10-05 WO disclosed
WO-2023054241-A1 LIPID NANOPARTICLE USED FOR DELIVERING NUCLEIC ACID TO BRAIN TISSUE 日油株式会社 2023-04-06 WO disclosed
WO-2023054243-A1 LIPID NANOPARTICLES HAVING CELL DIRECTIVITY 日油株式会社 2023-04-06 WO disclosed
WO-2023054242-A1 LIPID NANOPARTICLES USED TO TRANSPORT NUCLEIC ACIDS INTO LYMPHATIC ENDOTHELIUM CELLS 日油株式会社 2023-04-06 WO disclosed
WO-2022260678-A1 COMPOSITIONS AND METHODS FOR BIOLOGICAL DELIVERY VEHICLES DNALITE THERAPEUTICS, INC. (US) 2022-12-15 WO disclosed
US-20220000780-A1 NANODISCS FOR PREVENTING AND TREATING PATHOGEN INFECTIONS AND METHODS OF USE THEREOF NASR MAHMOUD (US) 2022-01-06 US disclosed
EP-3484912-B1 METHODS AND COMPOSITIONS RELATING TO COVALENTLY CIRCULARIZED NANODISCS HARVARD COLLEGE (US) 2021-10-20 EP disclosed
EP-3876909-A1 NANODISCS FOR PREVENTING AND TREATING PATHOGEN INFECTIONS AND METHODS OF USE THEREOF Nasr, Mahmoud (US) 2021-09-15 EP disclosed
US-20160346219-A1 PHOSPHOLIPID-COATED THERAPEUTIC AGENT NANOPARTICLES AND RELATED METHODS AUTOTELIC LLC (US) 2016-12-01 US disclosed
US-20160346220-A1 PHOSPHOLIPID-COATED THERAPEUTIC AGENT NANOPARTICLES AND RELATED METHODS AUTOTELIC LLC (US) 2016-12-01 US disclosed
US-20160346221-A1 PHOSPHOLIPID-COATED THERAPEUTIC AGENT NANOPARTICLES AND RELATED METHODS AUTOTELIC LLC (US) 2016-12-01 US disclosed
US-20150079156-A1 LIPOSOMAL DELIVERY SYSTEM THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2015-03-19 US disclosed
EP-2430151-A2 MENIGOCOCCUS VACCINE CONTAINING LIPOOLIGOSACCHARIDE (LOS) FROM MODIFIED STRAINS OF L6 IMMUNOTYPE NEISSERIA MENINGITIDIS Sanofi Pasteur (FR) 2012-03-21 EP disclosed
WO-2010130898-A2 MENIGOCOCCUS VACCINE CONTAINING LIPOOLIGOSACCHARIDE (LOS) FROM MODIFIED STRAINS OF L6 IMMUNOTYPE NEISSERIA MENINGITIDIS SANOFI PASTEUR (FR) 2010-11-18 WO disclosed
WO-2007005672-A2 TREATMENT AND PREVENTION OF RESPIRATORY DISEASES AND CONDITIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2007-01-11 WO disclosed
WO-2004087107-A1 CATIONIC LIPOSOME TARGETING SEBACEOUS GLANDS TRICHOGENE INC. (KR) 2004-10-14 WO disclosed
US-20020052310-A1 Particles for inhalation having sustained release properties MASSACHUSETTS INSTITUTE OF TECHNOLOGY THE PENN STATE RESEARCH FOUNDATION 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052310-A1 Particles for inhalation having sustained release properties SMPD4, SMPD2, SMPD3 LPAR1 112/4885LPAR3 88/4885LPAR2 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.