Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753952 | 0.87 | LPAR1 (0.58) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL10562812 | 0.86 | LPAR1 (0.60) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL10566866 | 0.86 | LPAR1 (0.60) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL2672057 | 0.86 | LPAR1 (0.60) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL17291865 | 0.81 | LPAR1 (0.47) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL10563457 | 0.80 | LPAR1 (0.53) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL3274160 | 0.80 | LPAR1 (0.53) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL667267 | 0.80 | LPAR1 (0.53) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| Ammonia Solution, Strong SCHEMBL6373587 | 0.77 | LPAR1 (0.60) | LPAR1LPAR3LPAR5LPAR2USP2 | |
| SCHEMBL1393763 | 0.76 | MAPT (0.50) | LPAR1LPAR3LPAR5LPAR2LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309186-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION | 2014-10-16 | — | — | US | disclosed |
| US-20110246081-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |