Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984825 | 0.79 | PRMT5 (0.49) | PRMT5WDR77JAK2CHEK1FLT3 | |
| SCHEMBL2460969 | 0.79 | PRMT5 (0.49) | PRMT5WDR77JAK2CHEK1FLT3 | |
| SCHEMBL23526034 | 0.79 | PRMT5 (0.49) | PRMT5WDR77JAK2CHEK1FLT3 | |
| SCHEMBL29945916 | 0.79 | PRMT5 (0.49) | PRMT5WDR77JAK2CHEK1FLT3 | |
| SCHEMBL24076903 | 0.78 | PRMT5 (0.48) | PRMT5WDR77JAK2CHEK1FLT3 | |
| SCHEMBL2029129 | 0.76 | JAK2 (0.63) | JAK2CHEK1FLT3PIM1DYRK1A | |
| SCHEMBL1330584 | 0.76 | PDPK1 (0.63) | JAK2CHEK1FLT3PIM1DYRK1A | |
| SCHEMBL29490946 | 0.76 | PDPK1 (0.63) | JAK2CHEK1FLT3PIM1DYRK1A | |
| SCHEMBL23914628 | 0.75 | PRMT5 (0.46) | PRMT5WDR77JAK2CHEK1FLT3 | |
| SCHEMBL30984977 | 0.75 | PRMT5 (0.46) | PRMT5WDR77JAK2CHEK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357162-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357162-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | NLRP3, NLRP1, NOD1 | PRMT5 1868/4885WDR77 1384/4885JAK2 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.