Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11860536 | 0.98 | TSHR (0.38) | TSHRCYP3A4NFKB1NPSR1SLC6A3 | |
| SCHEMBL253003 | 0.85 | CA1 (0.44) | NFKB1ALDH1A1CES1CES2CA1 | |
| SCHEMBL9851962 | 0.84 | CHRM1 (0.48) | TSHRCYP3A4NFKB1NPSR1SLC6A3 | |
| SCHEMBL11508090 | 0.81 | — | — | |
| SCHEMBL19604838 | 0.80 | TSHR (0.38) | TSHRCYP3A4NFKB1NPSR1SLC6A3 | |
| SCHEMBL28727343 | 0.80 | MEN1 (0.38) | TSHRTDP1ALDH1A1 | |
| SCHEMBL11508659 | 0.78 | CES2 (0.39) | TSHRCYP3A4NFKB1NPSR1SLC6A3 | |
| SCHEMBL11695301 | 0.77 | CES2 (0.37) | TSHRCYP3A4NFKB1NPSR1SLC6A3 | |
| SCHEMBL17674236 | 0.77 | POLB (0.39) | TSHRCYP3A4NFKB1NPSR1SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL11697179 | 0.77 | CES2 (0.37) | TSHRCYP3A4NFKB1NPSR1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253033-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | UNIV NORTH CAROLINA STATE (US) | 2018-03-15 | — | — | US | disclosed |
| US-9822123-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2017-11-21 | — | — | US | disclosed |
| US-20140371286-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-12-18 | — | — | US | disclosed |
| US-8664260-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-03-04 | — | — | US | disclosed |
| EP-1848778-B1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | UNIV NORTH CAROLINA STATE (US) | 2013-04-10 | — | — | EP | disclosed |
| US-20120232463-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-09-13 | — | — | US | disclosed |
| US-8173691-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173692-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-05-08 | — | — | US | disclosed |
| US-20090226467-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090191130-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-30 | — | — | US | disclosed |
| US-7534807-B2 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-19 | — | — | US | disclosed |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-31 | — | — | US | disclosed |
| US-4159996-A | Preparation of alkane diamines | TEXACO INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-3969322-A | AMINOESTER POLYMER FROM A NITROKETONIZED POLYMER AND TERT-AMINO ALCOHOL | TEXACO INC. (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253033-B2 | De novo synthesis of bacteriochlorins | BCL6, ALDH1A2, ALAD | TSHR 4491/4885CYP3A4 3866/4885NFKB1 1160/4885 |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | PCNA, SCD, BCL6 | TSHR 4693/4885CYP3A4 3742/4885NFKB1 387/4885 |
| US-20120232463-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TSHR 4491/4885CYP3A4 3866/4885NFKB1 1160/4885 |
| US-20140371286-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TSHR 4491/4885CYP3A4 3866/4885NFKB1 1160/4885 |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TSHR 4491/4885CYP3A4 3866/4885NFKB1 1160/4885 |
| US-20090226467-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TSHR 4491/4885CYP3A4 3866/4885NFKB1 1160/4885 |
| US-20090191130-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TSHR 4491/4885CYP3A4 3866/4885NFKB1 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.