Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.45 |
| ▸ | NOS1 | P29475 | 6/20 | 0.45 |
| ▸ | NOS2 | P35228 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DDX3X | O00571 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722461 | 0.76 | KCNH2 (0.48) | NOS2KCNH2SLC6A4 | |
| SCHEMBL17858892 | 0.73 | NOS2 (0.36) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL9125293 | 0.72 | NOS3 (0.40) | NOS3NOS1NOS2SIGMAR1HRH3 | |
| SCHEMBL16132008 | 0.72 | HRH3 (0.35) | SIGMAR1HRH3 | |
| SCHEMBL20342484 | 0.71 | HRH1 (0.39) | HRH3HRH4 | |
| SCHEMBL28993548 | 0.70 | NOS3 (0.39) | NOS3NOS1NOS2SIGMAR1HRH3 | |
| SCHEMBL522952 | 0.69 | KCNH2 (0.55) | NOS3NOS1NOS2SIGMAR1KCNH2 | |
| SCHEMBL13051982 | 0.69 | APLNR (0.39) | — | |
| SCHEMBL7072554 | 0.68 | — | — | |
| SCHEMBL28315278 | 0.67 | NOS3 (0.39) | NOS3NOS1NOS2SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205645-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |