SCHEMBL26751632

SCHEMBL26751632

CCCCCCC(=O)OCC1OC(n2ccc(=O)[nH]c2=O)C(OC(C)=O)C1OC(C)=O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
THRB P10828 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
TK2 O00142 4/20 0.48
P2RY12 Q9H244 3/20 0.47
P2RY2 P41231 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
P2RY1 P47900 1/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25402244 1.00 LMNA (0.50) LMNATHRBSMN1; SMN2HIF1ATK2
SCHEMBL9069552 0.95 TK2 (0.53) LMNATHRBSMN1; SMN2HIF1ATK2
SCHEMBL9069522 0.91 CA12 (0.49) LMNATHRBSMN1; SMN2HIF1ATK2
SCHEMBL5566835 0.87 CA12 (0.47) LMNATHRBSMN1; SMN2HIF1AP2RY12
Uridine Triacetate SCHEMBL15279673 0.87 LMNA (0.64) LMNATHRBSMN1; SMN2HIF1AP2RY12
Uridine Triacetate SCHEMBL12900042 0.87 LMNA (0.64) LMNATHRBSMN1; SMN2HIF1AP2RY12
Uridine Triacetate SCHEMBL16455208 0.87 LMNA (0.64) LMNATHRBSMN1; SMN2HIF1AP2RY12
Uridine Triacetate SCHEMBL12928917 0.87 LMNA (0.64) LMNATHRBSMN1; SMN2HIF1AP2RY12
Uridine Triacetate SCHEMBL10350038 0.87 LMNA (0.64) LMNATHRBSMN1; SMN2HIF1AP2RY12
Uridine Triacetate SCHEMBL14950624 0.87 LMNA (0.64) LMNATHRBSMN1; SMN2HIF1AP2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357304-A1 2′,3′-Diacetyluridine Substituted With Acetoacetyl at the 5′ Position WELLSTAT THERAPEUTICS CORPORATION 2023-11-09 US disclosed
US-20230357304-A1 2′,3′-Diacetyluridine Substituted With Acetoacetyl at the 5′ Position WELLSTAT THERAPEUTICS CORPORATION 2023-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357304-A1 2′,3′-Diacetyluridine Substituted With Acetoacetyl at the 5′ Position ACAT1, ACADVL, ACAA2 LMNA 3476/4885THRB 3021/4885SMN1; SMN2 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.