Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.34 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22047521 | 0.89 | CRBN (0.47) | CRBNARIKZF2IKZF1DDB1 | |
| SCHEMBL22873401 | 0.87 | CRBN (0.53) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL25059028 | 0.86 | CRBN (0.56) | CRBNARIKZF2IKZF1DDB1 | |
| SCHEMBL20076201 | 0.84 | CRBN (0.53) | CRBNDDB1IKZF3TNFDRD2 | |
| SCHEMBL31447949 | 0.79 | CRBN (0.66) | CRBNARDDB1IKZF3TNF | |
| SCHEMBL31447951 | 0.79 | CRBN (0.63) | CRBNARDDB1IKZF3TNF | |
| SCHEMBL20046709 | 0.78 | CRBN (0.43) | CRBNARDDB1ESR1IKZF3 | |
| SCHEMBL22692241 | 0.78 | CRBN (0.43) | CRBNARIKZF2DDB1ESR1 | |
| SCHEMBL22565934 | 0.77 | CRBN (0.47) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL23138921 | 0.77 | CRBN (0.47) | CRBNDDB1IKZF3TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205892-A1 | CDK INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-11-02 | — | — | WO | disclosed |