Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | KARS1 | Q15046 | 4/20 | 0.77 |
| ▸ | RXRA | P19793 | 1/20 | 0.77 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.77 |
| ▸ | CDK2 | P24941 | 1/20 | 0.77 |
| ▸ | RXRB | P28702 | 1/20 | 0.77 |
| ▸ | RXRG | P48443 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.65 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.65 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.65 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3462324 | 0.88 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL2989705 | 0.88 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL14479889 | 0.88 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL30383762 | 0.88 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL14653170 | 0.87 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL15313390 | 0.87 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL18019015 | 0.87 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL20061641 | 0.87 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL2603437 | 0.87 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Dehydroabietic Acid SCHEMBL15744753 | 0.87 | KARS1 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770442-B2 | Self-assembling amphiphilic polymers as anti-cancer agents | ALLEXCEL INC. (US) | 2017-09-26 | — | — | US | disclosed |
| EP-2120974-B1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | ALLEXCEL INC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2167103-B1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTICANCER AGENTS | ALLEXCEL INC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-1979407-B1 | SOLUBILIZATION AND TARGETED DELIVERY OF DRUGS WITH SELF-ASSEMBLING AMPHIPHILIC POLYMERS | ALLEXCEL INC (US) | 2014-08-06 | — | — | EP | disclosed |
| US-8173764-B2 | Solubilization and targeted delivery of drugs with self-assembling amphiphilic polymers | ALLEXCEL INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20100260743-A1 | Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers | ALLEXCEL, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100239659-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-CANCER AGENTS | ALLEXCEL., INC. (US) | 2010-09-23 | — | — | US | disclosed |
| EP-2167103-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTICANCER AGENTS | Allexcel, Inc. (US) | 2010-03-31 | — | — | EP | disclosed |
| US-20100008938-A1 | SELF ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | ALLEXCEL, INC. | 2010-01-14 | — | — | US | disclosed |
| EP-2120974-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | Allexcel, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2009011702-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTICANCER AGENTS | ALLEXCEL, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| EP-1979407-A1 | SOLUBILIZATION AND TARGETED DELIVERY OF DRUGS WITH SELF-ASSEMBLING AMPHIPHILIC POLYMERS | Allexcel, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2008091246-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | ALLEXCEL, INC. (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2007084126-A1 | SOLUBILIZATION AND TARGETED DELIVERY OF DRUGS WITH SELF-ASSEMBLING AMPHIPHILIC POLYMERS | ALLEXCEL, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100008938-A1 | SELF ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS | PICALM, CLTA, HAVCR2 | CYP3A4 4133/4885LMNA 2356/4885KARS1 1865/4885 |
| US-20100239659-A1 | SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTI-CANCER AGENTS | CD44, EPCAM, EGFR | CYP3A4 4163/4885LMNA 2786/4885KARS1 2920/4885 |
| US-20100260743-A1 | Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers | CD44, ABCG2, ABCC1 | CYP3A4 758/4885LMNA 1169/4885KARS1 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.